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Evaluation of treatment efficacy using a Bayesian mixture piecewise linear model of longitudinal biomarkers
Prostate-specific antigen (PSA) is a widely used marker in clinical trials for patients with prostate cancer. We develop a mixture model to estimate longitudinal PSA trajectory in response to treatment. The model accommodates subjects responding and not responding to therapy through a mixture of two...
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| Publicado no: | Stat Med |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995342/ https://ncbi.nlm.nih.gov/pubmed/25630845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6445 |
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