A high throughput whole blood assay for analysis of multiple antigen-specific T cell responses in human Mycobacterium tuberculosis infection

Antigen (Ag)-specific CD4 and CD8 T cells are important components of the immune response to Mycobacterium tuberculosis (Mtb), yet little information is currently known regarding how the breadth, specificity, phenotype and function of Mtb-specific T cells correlate with Mtb infection outcome in huma...

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Publicado en:J Immunol
Autores principales: Whatney, Wendy E., Gandhi, Neel R., Lindestam Arlehamn, Cecilia S., Nizam, Azhar, Wu, Hao, Quezada, Melanie J., Campbell, Angela, Allana, Salim, Kabongo, Mbuyi Madeleine, Khayumbi, Jeremiah, Muchiri, Benson, Ongalo, Joshua, Tonui, Joan, Sasser, Loren E., Fergus, Tawania J., Ouma, Gregory Sadat, Ouma, Samuel Gurrion, Beck, Allison A., Mulligan, Mark J., Oladele, Alawode, Kaushal, Deepak, Cain, Kevin P., Waller, Lance, Blumberg, Henry M., Altman, John D., Ernst, Joel D., Rengarajan, Jyothi, Day, Cheryl L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995335/
https://ncbi.nlm.nih.gov/pubmed/29540577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701737
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