A high throughput whole blood assay for analysis of multiple antigen-specific T cell responses in human Mycobacterium tuberculosis infection

Antigen (Ag)-specific CD4 and CD8 T cells are important components of the immune response to Mycobacterium tuberculosis (Mtb), yet little information is currently known regarding how the breadth, specificity, phenotype and function of Mtb-specific T cells correlate with Mtb infection outcome in huma...

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Veröffentlicht in:J Immunol
Hauptverfasser: Whatney, Wendy E., Gandhi, Neel R., Lindestam Arlehamn, Cecilia S., Nizam, Azhar, Wu, Hao, Quezada, Melanie J., Campbell, Angela, Allana, Salim, Kabongo, Mbuyi Madeleine, Khayumbi, Jeremiah, Muchiri, Benson, Ongalo, Joshua, Tonui, Joan, Sasser, Loren E., Fergus, Tawania J., Ouma, Gregory Sadat, Ouma, Samuel Gurrion, Beck, Allison A., Mulligan, Mark J., Oladele, Alawode, Kaushal, Deepak, Cain, Kevin P., Waller, Lance, Blumberg, Henry M., Altman, John D., Ernst, Joel D., Rengarajan, Jyothi, Day, Cheryl L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995335/
https://ncbi.nlm.nih.gov/pubmed/29540577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701737
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