Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells

Alveolar rhabdomyosarcoma (aRMS) is an aggressive subtype of the most common soft tissue cancer in children. A hallmark of aRMS tumors is incomplete myogenic differentiation despite expression of master myogenic regulators such as MyoD. We previously reported that histone methyltransferase KMT1A sup...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Wolff, David W., Lee, Min-Hyung, Jothi, Mathivanan, Mal, Munmun, Li, Fengzhi, Mal, Asoke K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995248/
https://ncbi.nlm.nih.gov/pubmed/29899822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25376
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