(111)In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells

Radiolabelled, drug-loaded nanoparticles may combine the theranostic properties of radionuclides, the controlled release of chemotherapy and cancer cell targeting. Here, we report the preparation of poly(lactic-co-glycolic acid) (PLGA) nanoparticles surface conjugated to DTPA-hEGF (DTPA = diethylene...

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Detalhes bibliográficos
Publicado no:Nanoscale
Main Authors: Gill, Martin R., Menon, Jyothi U., Jarman, Paul J., Owen, Joshua, Skaripa-Koukelli, Irini, Able, Sarah, Thomas, Jim A., Carlisle, Robert, Vallis, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994990/
https://ncbi.nlm.nih.gov/pubmed/29808844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7nr09606b
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