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In vivo mitotic spindle scaling can be modulated by changing the levels of a single protein: the microtubule polymerase XMAP215

In many organisms, early embryonic development is characterized by a series of reductive cell divisions that result in rapid increases in cell number and concomitant decreases in cell size. Intracellular organelles, such as the nucleus and mitotic spindle, also become progressively smaller during th...

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Pubblicato in:Mol Biol Cell
Autori principali: Milunovic´-Jevtic´, Ana, Jevtic´, Predrag, Levy, Daniel L., Gatlin, J. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994900/
https://ncbi.nlm.nih.gov/pubmed/29851557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-01-0011
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