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Enantioselective synthesis of amines by combining photoredox and enzymatic catalysis in a cyclic reaction network

Visible light-driven reduction of imines to enantioenriched amines in aqueous solution is demonstrated for the first time. Excitation of a new water-soluble variant of the widely used [Ir(ppy)(3)] (ppy = 2-phenylpyridine) photosensitizer in the presence of a cyclic imine affords a highly reactive α-...

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Publicat a:Chem Sci
Autors principals: Guo, Xingwei, Okamoto, Yasunori, Schreier, Mirjam R., Ward, Thomas R., Wenger, Oliver S.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994792/
https://ncbi.nlm.nih.gov/pubmed/29938035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc01561a
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