Next generation immune-checkpoints for cancer therapy

The discovery and clinical application of immune-checkpoint inhibitors has dramatically improved the treatments, outcomes and therapeutic concepts in multiple tumor settings. This breakthrough was mainly based on monoclonal antibodies blocking the inhibitory molecule CTLA-4 and or the PD-1/PD-L1 axi...

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Bibliographic Details
Published in:J Thorac Dis
Main Authors: Donini, Chiara, D’Ambrosio, Lorenzo, Grignani, Giovanni, Aglietta, Massimo, Sangiolo, Dario
Format: Artigo
Language:Inglês
Published: AME Publishing Company 2018
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994499/
https://ncbi.nlm.nih.gov/pubmed/29951308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2018.02.79
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