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Functional importance of Glutamate-445 and Glutamate-99 in proton-coupled electron transfer during oxygen reduction by cytochrome bd from Escherichia coli

The recent X-ray structure of the cytochrome bd respiratory oxygen reductase showed that two of the three heme components, heme d and heme b(595), have glutamic acid as an axial ligand. No other native heme proteins are known to have glutamic acid axial ligands. In this work, site-directed mutagenes...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Murali, Ranjani, Gennis, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994205/
https://ncbi.nlm.nih.gov/pubmed/29719208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2018.04.012
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