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Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase

Molecular oxygen acts as the terminal electron sink in the respiratory chains of aerobic organisms. Cytochrome c oxidase in the inner membrane of mitochondria and the plasma membrane of bacteria catalyzes the reduction of oxygen to water, and couples the free energy of the reaction to proton pumping...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Sharma, Vivek, Enkavi, Giray, Vattulainen, Ilpo, Róg, Tomasz, Wikström, Mårten
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343153/
https://ncbi.nlm.nih.gov/pubmed/25646428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409543112
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