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Effect of metabolic syndrome and aging on Ca(2+) dysfunction in coronary smooth muscle and coronary artery disease severity in Ossabaw miniature swine

BACKGROUND: Metabolic syndrome (MetS) and aging are prevalent risk factors for coronary artery disease (CAD) and contribute to the etiology of CAD, including dysregulation of Ca(2+) handling mechanisms in coronary smooth muscle (CSM). The current study tested the hypothesis that CAD severity and CSM...

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Опубликовано в: :Exp Gerontol
Главные авторы: Badin, Jill K., Bruning, Rebecca S., Sturek, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994201/
https://ncbi.nlm.nih.gov/pubmed/29730333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2018.04.024
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