Alloxan-induced diabetes exacerbates coronary atherosclerosis and calcification in Ossabaw miniature swine with metabolic syndrome

BACKGROUND: There is a preponderance of evidence implicating diabetes with increased coronary artery disease (CAD) and calcification (CAC) in human patients with metabolic syndrome (MetS), but the effect of diabetes on CAD severity in animal models remains controversial. We investigated whether diab...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Badin, Jill K., Kole, Ayeeshik, Stivers, Benjamin, Progar, Victor, Pareddy, Anisha, Alloosh, Mouhamad, Sturek, Michael
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5845376/
https://ncbi.nlm.nih.gov/pubmed/29523165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1431-9
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