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DrImpute: imputing dropout events in single cell RNA sequencing data

BACKGROUND: The single cell RNA sequencing (scRNA-seq) technique begin a new era by allowing the observation of gene expression at the single cell level. However, there is also a large amount of technical and biological noise. Because of the low number of RNA transcriptomes and the stochastic nature...

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Pubblicato in:BMC Bioinformatics
Autori principali: Gong, Wuming, Kwak, Il-Youp, Pota, Pruthvi, Koyano-Nakagawa, Naoko, Garry, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5994079/
https://ncbi.nlm.nih.gov/pubmed/29884114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2226-y
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