Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts

Direct lineage reprogramming can convert readily available cells in the body into desired cell types for cell replacement therapy. This is usually achieved through forced activation or repression of lineage-defining factors or pathways. In particular, reprogramming toward the pancreatic β cell fate...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Wang, Yuhan, Dorrell, Craig, Naugler, Willscott E., Heskett, Michael, Spellman, Paul, Li, Bin, Galivo, Feorillo, Haft, Annelise, Wakefield, Leslie, Grompe, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993989/
https://ncbi.nlm.nih.gov/pubmed/29550076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.02.014
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