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Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts

Direct lineage reprogramming can convert readily available cells in the body into desired cell types for cell replacement therapy. This is usually achieved through forced activation or repression of lineage-defining factors or pathways. In particular, reprogramming toward the pancreatic β cell fate...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Wang, Yuhan, Dorrell, Craig, Naugler, Willscott E., Heskett, Michael, Spellman, Paul, Li, Bin, Galivo, Feorillo, Haft, Annelise, Wakefield, Leslie, Grompe, Markus
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993989/
https://ncbi.nlm.nih.gov/pubmed/29550076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.02.014
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