Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells

In the developing nervous system, neural stem cells are polarized and maintain an apical domain facing a central lumen. The presence of apical membrane is thought to have a profound influence on maintaining the stem cell state. With the onset of neurogenesis, cells lose their polarization, and the c...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Medelnik, Jan-Philip, Roensch, Kathleen, Okawa, Satoshi, del Sol, Antonio, Chara, Osvaldo, Mchedlishvili, Levan, Tanaka, Elly M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993681/
https://ncbi.nlm.nih.gov/pubmed/29779899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.04.018
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