Perfusion alterations converge with patterns of pathological spread in TDP-43 proteinopathies

Amyotrophic lateral sclerosis (ALS) and the behavioural variant of frontotemporal dementia (bvFTD) commonly share the presence of TDP-43 inclusions. Structural MRI studies demonstrated evidence for TDP-43 pathology spread, but while structural imaging usually reveals overt neuronal loss, perfusion i...

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Gepubliceerd in:Neurobiol Aging
Hoofdauteurs: Ferraro, Pilar M., Jester, Charles, Olm, Christopher A., Placek, Katerina, Agosta, Federica, Elman, Lauren, McCluskey, Leo, Irwin, David J., Detre, John A., Filippi, Massimo, Grossman, Murray, McMillan, Corey T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993674/
https://ncbi.nlm.nih.gov/pubmed/29751289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.04.008
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