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NMMHC IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signalling pathways in the endothelium

Non-muscle myosin heavy chain IIA (NMMHC IIA) has been shown to be involved in thrombus formation and inflammatory microparticle release in endothelial cells. However, the role of NMMHC IIA in regulating the expression of tissue factor (TF) and deep venous thrombosis remains to be elucidated. In the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Thromb Haemost
Hauptverfasser: Zhai, Kefeng, Tang, Youmei, Zhang, Yuanyuan, Li, Fang, Wang, Yan, Cao, Zhengyu, Yu, Jun, Kou, Junping, Yu, Boyang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993197/
https://ncbi.nlm.nih.gov/pubmed/25881103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH14-10-0880
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