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NMMHC IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signalling pathways in the endothelium

Non-muscle myosin heavy chain IIA (NMMHC IIA) has been shown to be involved in thrombus formation and inflammatory microparticle release in endothelial cells. However, the role of NMMHC IIA in regulating the expression of tissue factor (TF) and deep venous thrombosis remains to be elucidated. In the...

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Detalhes bibliográficos
Publicado no:Thromb Haemost
Main Authors: Zhai, Kefeng, Tang, Youmei, Zhang, Yuanyuan, Li, Fang, Wang, Yan, Cao, Zhengyu, Yu, Jun, Kou, Junping, Yu, Boyang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993197/
https://ncbi.nlm.nih.gov/pubmed/25881103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH14-10-0880
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