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The saponin DT-13 Attenuates Tumor Necrosis Factor-α-induced Vascular Inflammation Associated with Src/NF-кB/MAPK Pathway Modulation

This study aimed to explore the effect of DT-13 (25(R,S)-ruscogenin- 1-O- [β-d-glucopyranosyl- (1→2)][β-d-xylopyranosyl-(1→3)]-β -d- fucopyranoside) on tumor necrosis factor (TNF)-α-induced vascular inflammation and the potential molecular mechanisms. In vitro, DT-13 suppressed TNF-α-induced adhesio...

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Podrobná bibliografie
Vydáno v:Int J Biol Sci
Hlavní autoři: Zhang, Yuanyuan, Sun, Minhui, Han, Yuwei, Zhai, Kefeng, Tang, Youmei, Qin, Xiaoying, Cao, Zhengyu, Yu, Boyang, Kou, Junping
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495414/
https://ncbi.nlm.nih.gov/pubmed/26157351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.11635
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