Cdc42 Regulates Neuronal Polarity during Cerebellar Axon Formation and Glial-Guided Migration

CNS cortical histogenesis depends on polarity signaling pathways that regulate cell adhesion and motility. Here we report that conditional deletion of the Rho GTPase Cdc42 in cerebellar granule cell precursors (GCPs) results in abnormalities in cerebellar foliation revealed by iDISCO clearing method...

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Bibliographic Details
Published in:iScience
Main Authors: Govek, Eve-Ellen, Wu, Zhuhao, Acehan, Devrim, Molina, Henrik, Rivera, Keith, Zhu, Xiaodong, Fang, Yin, Tessier-Lavigne, Marc, Hatten, Mary Elizabeth
Format: Artigo
Language:Inglês
Published: Elsevier 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993048/
https://ncbi.nlm.nih.gov/pubmed/29888765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.01.004
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