Cdc42 Regulates Neuronal Polarity during Cerebellar Axon Formation and Glial-Guided Migration

CNS cortical histogenesis depends on polarity signaling pathways that regulate cell adhesion and motility. Here we report that conditional deletion of the Rho GTPase Cdc42 in cerebellar granule cell precursors (GCPs) results in abnormalities in cerebellar foliation revealed by iDISCO clearing method...

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Detaylı Bibliyografya
Yayımlandı:iScience
Asıl Yazarlar: Govek, Eve-Ellen, Wu, Zhuhao, Acehan, Devrim, Molina, Henrik, Rivera, Keith, Zhu, Xiaodong, Fang, Yin, Tessier-Lavigne, Marc, Hatten, Mary Elizabeth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993048/
https://ncbi.nlm.nih.gov/pubmed/29888765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.01.004
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