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Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration

The mammalian liver has a remarkable capacity for repair following injury. Removal of up to two-third of liver mass results in a series of events that include extracellular matrix remodeling, coordinated hepatic cell cycle re-entry, restoration of liver mass and tissue remodeling to return the damag...

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Vydáno v:Exp Mol Med
Hlavní autoři: Lu, Li, Finegold, Milton J, Johnson, Randy L
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992983/
https://ncbi.nlm.nih.gov/pubmed/29303509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.205
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