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The effect of different combinations of vascular, dependency and cognitive endpoints on the sample size required to detect a treatment effect in trials of treatments to improve outcome after lacunar and non-lacunar ischaemic stroke
BACKGROUND: Endpoints that are commonly used in trials of moderate/severe stroke may be less frequent in patients with minor, non-disabling stroke thus inflating sample sizes. We tested whether trial efficiency might be improved with composite endpoints. METHODS: We prospectively recruited patients...
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| 發表在: | Eur Stroke J |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
SAGE Publications
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5992736/ https://ncbi.nlm.nih.gov/pubmed/29900411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2396987317728854 |
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