Deep sequencing of human papillomavirus positive loco-regionally advanced oropharyngeal squamous cell carcinomas reveals novel mutational signature

BACKGROUND: The genetic profile for human papilloma virus positive (HPV+) oropharyngeal squamous cell carcinomas (OPSCC) remains largely unknown. The purpose of this study was to sequence tissue material from a large cohort of locoregionally-advanced HPV+ OPSCCs. METHODS: We performed targeted deep...

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Pubblicato in:BMC Cancer
Autori principali: Grønhøj, Christian, Jensen, David H., Agander, Tina, Kiss, Katalin, Høgdall, Estrid, Specht, Lena, Bagger, Frederik Otzen, Nielsen, Finn Cilius, von Buchwald, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992702/
https://ncbi.nlm.nih.gov/pubmed/29879932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4567-3
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