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An efficient new method for the synthesis of 3-[(18)F]fluoro-4-aminopyridine via Yamada-Curtius rearrangement

4-Aminopyridine is a clinically approved drug to improve motor symptoms in multiple sclerosis. A fluorine-18-labeled derivative of this drug, 3-[(18)F]fluoro-4-aminopyridine, is currently under investigation for positron emission tomography (PET) imaging of demyelination. Herein, the Yamada-Curtius...

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書目詳細資料
發表在:J Labelled Comp Radiopharm
Main Authors: Basuli, Falguni, Zhang, Xiang, Brugarolas, Pedro, Reich, Daniel S., Swenson, Rolf E.
格式: Artigo
語言:Inglês
出版: 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992582/
https://ncbi.nlm.nih.gov/pubmed/28870001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3560
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