miR-199a-3p Modulates MTOR and PAK4 Pathways and Inhibits Tumor Growth in a Hepatocellular Carcinoma Transgenic Mouse Model

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. Prognosis is poor, and therapeutic options are limited. MicroRNAs (miRNAs) have emerged as potential therapeutic molecules against cancer. Here, we investigated the therapeutic efficacy of miR-199a-3p, an m...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Ther Nucleic Acids
Main Authors: Callegari, Elisa, D’Abundo, Lucilla, Guerriero, Paola, Simioni, Carolina, Elamin, Bahaeldin K., Russo, Marta, Cani, Alice, Bassi, Cristian, Zagatti, Barbara, Giacomelli, Luciano, Blandamura, Stella, Moshiri, Farzaneh, Ultimo, Simona, Frassoldati, Antonio, Altavilla, Giuseppe, Gramantieri, Laura, Neri, Luca Maria, Sabbioni, Silvia, Negrini, Massimo
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Gene & Cell Therapy 2018
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992479/
https://ncbi.nlm.nih.gov/pubmed/29858083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.04.002
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