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Natively unfolded FG-repeats stabilize the structure of the nuclear pore complex
Nuclear pore complexes (NPCs) are ~100 MDa transport channels assembled from multiple copies of ~30 nucleoporins (Nups). One third of these Nups contain phenylalanine-glycine (FG)-rich repeats forming a diffusion barrier, which is selectively permeable for nuclear transport receptors that interact w...
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| Veröffentlicht in: | Cell |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5992322/ https://ncbi.nlm.nih.gov/pubmed/29033133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.033 |
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