Natively unfolded FG-repeats stabilize the structure of the nuclear pore complex

Nuclear pore complexes (NPCs) are ~100 MDa transport channels assembled from multiple copies of ~30 nucleoporins (Nups). One third of these Nups contain phenylalanine-glycine (FG)-rich repeats forming a diffusion barrier, which is selectively permeable for nuclear transport receptors that interact w...

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Udgivet i:Cell
Main Authors: Onischenko, Evgeny, Tang, Jeffrey H., Andersen, Kasper R., Knockenhauer, Kevin E., Vallotton, Pascal, Derrer, Carina P., Kralt, Annemarie, Mugler, Christopher F., Chan, Leon Y., Schwartz, Thomas U., Weis, Karsten
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992322/
https://ncbi.nlm.nih.gov/pubmed/29033133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.09.033
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