IL-4 Is a Key Requirement for IL-4- and IL-4/IL-13-Expressing CD4 Th2 Subsets in Lung and Skin

Although IL-4 is long associated with CD4 Th2 immune responses, its role in Th2 subset development in non-lymphoid tissues is less clear. We sought to better define IL-4’s role in CD4 Th2 responses by using transgenic mice that express a dual IL-4 AmCyan/IL-13 DsRed (IL-4AC/IL-13DR) fluorescent repo...

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Vydáno v:Front Immunol
Hlavní autoři: Prout, Melanie Sarah, Kyle, Ryan L., Ronchese, Franca, Le Gros, Graham
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992292/
https://ncbi.nlm.nih.gov/pubmed/29910811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01211
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