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Thymic stromal lymphopoietin drives the development of IL-13(+) Th2 cells

T helper 2 (Th2) cells are pivotal in the development of allergy. Allergen exposure primes IL-4(+) Th2 cells in lymph node, but production of effector cytokines including IL-5 and IL-13 is thought to require additional signals from antigen and the environment. Here we report that a substantial propo...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Ochiai, Sotaro, Jagot, Ferdinand, Kyle, Ryan L., Hyde, Evelyn, White, Ruby F., Prout, Melanie, Schmidt, Alfonso J., Yamane, Hidehiro, Lamiable, Olivier, Le Gros, Graham, Ronchese, Franca
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798347/
https://ncbi.nlm.nih.gov/pubmed/29339496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714348115
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