High Body Mass Index is Associated with Increased Risk of Treatment Failure and Surgery in Biologic-treated Patients with Ulcerative Colitis

BACKGROUND: Though pharmacokinetic studies suggest accelerated biologic drug clearance with increasing body weight, evidence of obesity’s impact on clinical outcomes in biologic-treated patients with ulcerative colitis (UC) is inconsistent. AIMS: We evaluated the impact of obesity on real world resp...

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Detalhes bibliográficos
Publicado no:Aliment Pharmacol Ther
Main Authors: Kurnool, Soumya, Nguyen, Nghia H., Proudfoot, James, Dulai, Parambir S., Boland, Brigid S., Casteele, Niels Vande, Evans, Elisabeth, Grunvald, Eduardo L., Zarrinpar, Amir, Sandborn, William J., Singh, Siddharth
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992082/
https://ncbi.nlm.nih.gov/pubmed/29665045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.14665
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