Targeting skeletal endothelium to ameliorate bone loss

Recent studies have identified a specialized subset of CD31(hi)EMCN(hi) vascular endothelium that positively regulates bone formation. However, it remains unclear how CD31(hi)EMCN(hi) endothelium levels are coupled to anabolic bone formation. Mice with an osteoblast-specific deletion of Shn3, which...

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Publicado no:Nat Med
Main Authors: Xu, Ren, Yallowitz, Alisha, Qin, An, Wu, Zhuhao, Shin, Dong Yeon, Kim, Jung-Min, Debnath, Shawon, Ji, Gang, Bostrom, Mathias P., Yang, Xu, Zhang, Chao, Dong, Han, Kermani, Pouneh, Lalani, Sarfaraz, Li, Na, Liu, Yifang, Poulos, Michael G., Wach, Amanda, Zhang, Yi, Inoue, Kazuki, Di Lorenzo, Annarita, Zhao, Baohong, Butler, Jason M., Shim, Jae-Hyuck, Glimcher, Laurie H., Greenblatt, Matthew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5992080/
https://ncbi.nlm.nih.gov/pubmed/29785024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0020-z
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