SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts

Hedgehog signaling is essential for bone formation, including functioning as a means for the growth plate to drive skeletal mineralization. However, the mechanisms regulating hedgehog signaling specifically in bone-forming osteoblasts are largely unknown. Here, we identified SLIT and NTRK-like prote...

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發表在:Nat Commun
Main Authors: Sun, Jun, Shin, Dong Yeon, Eiseman, Mark, Yallowitz, Alisha R., Li, Na, Lalani, Sarfaraz, Li, Zan, Cung, Michelle, Bok, Seoyeon, Debnath, Shawon, Marquez, Sofia Jenia, White, Tommy E., Khan, Abdul G., Lorenz, Ivo C., Shim, Jae-Hyuck, Lee, Francis S., Xu, Ren, Greenblatt, Matthew B.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322311/
https://ncbi.nlm.nih.gov/pubmed/34326333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24819-w
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