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Immune checkpoint blockade in infectious diseases
The up-regulation of immune checkpoint molecules, such as PD-1 and CTLA4 on immune cells occur during acute infections, such as malaria, as well as during chronic persistent viral infections, including HIV and hepatitis B virus (HBV). These pathways are important for preventing immune-driven patholo...
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| Publicado en: | Nat Rev Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5991909/ https://ncbi.nlm.nih.gov/pubmed/28990586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2017.112 |
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