Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages

NKG2D is an important immunoreceptor expressed on the surface of NK cells and some T cells. NKG2D recognizes a set of ligands typically expressed on infected or transformed cells, but recent studies have also documented NKG2D ligands on subsets of host non-tumor cells in tumor-bearing animals and hu...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Thompson, Thornton W, Jackson, Benjamin T, Li, P Jonathan, Wang, Jiaxi, Kim, Alexander Byungsuk, Huang, Kristen Ting Hui, Zhang, Lily, Raulet, David H
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
Assuntos:
Cancer Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991831/
https://ncbi.nlm.nih.gov/pubmed/29757143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32919
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