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Folate receptor 1 (FOLR1) targeted chimeric antigen receptor (CAR) T cells for the treatment of gastric cancer

Gastric cancer is a malignancy that has a high mortality rate. Although progress has been made in the treatment of gastric cancer, many patients experience cancer recurrence and metastasis. Folate receptor 1 (FOLR1) is overexpressed on the cell surface in over one-third of gastric cancer patients, b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kim, Minsung, Pyo, Suhkneung, Kang, Chung Hyo, Lee, Chong Ock, Lee, Heung Kyoung, Choi, Sang Un, Park, Chi Hoon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991383/
https://ncbi.nlm.nih.gov/pubmed/29874279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198347
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