Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer

BACKGROUND: Prostate cancer remains the second leading cause of cancer related death in men. Immune check point blocking antibodies have revolutionized treatment of multiple solid tumors, but results in prostate cancer remain marginal. Previous reports have suggested that local therapies, in particu...

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Veröffentlicht in:Prostate Cancer Prostatic Dis
Hauptverfasser: Benzon, Benjamin, Glavaris, Stephanie A., Simons, Brian W., Hughes, Robert M., Ghabili, Kamyar, Mullane, Patrick, Miller, Rebecca, Nugent, Katriana, Shinder, Brian, Tosoian, Jeffrey, Fuchs, Ephraim J., Tran, Phuoc T., Hurley, Paula J., Vuica-Ross, Milena, Schaeffer, Edward M., Drake, Charles G., Ross, Ashley E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990963/
https://ncbi.nlm.nih.gov/pubmed/29556048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41391-018-0035-z
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