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Capillary HILIC-MS: A New Tool for Sensitive Top-Down Proteomics

[Image: see text] Recent progress in top-down proteomics has driven the demand for chromatographic methods compatible with mass spectrometry (MS) that can separate intact proteins. Hydrophilic interaction liquid chromatography (HILIC) has recently shown good potential for the characterization of gly...

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Détails bibliographiques
Publié dans:Anal Chem
Auteurs principaux: Gargano, Andrea F.G., Roca, Liana S., Fellers, Ryan T., Bocxe, Max, Domínguez-Vega, Elena, Somsen, Govert W.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2018
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990932/
https://ncbi.nlm.nih.gov/pubmed/29722972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b00382
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