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Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age
We have recently shown that male Rhes knockout (KO) mice develop a mild form of spontaneous Parkinson’s disease (PD)-like phenotype, characterized by motor impairment and a decrease in nigrostriatal dopamine (DA) neurons. Experimental evidence has implicated neuroinflammation in PD progression, and...
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| Publicat a: | Front Aging Neurosci |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5990628/ https://ncbi.nlm.nih.gov/pubmed/29904346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00163 |
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