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The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells

BACKGROUND: T follicular helper (Tfh) cells are key players in the production of antibody-producing B cells via the germinal center reaction. Therapeutic strategies targeting Tfh cells are important where antibody formation is implicated in disease, such as transplant rejection and autoimmune diseas...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Wallin, Elizabeth F., Hill, Danika L., Linterman, Michelle A., Wood, Kathryn J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990622/
https://ncbi.nlm.nih.gov/pubmed/29904381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01184
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