RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

T-cells are known to be intimately involved in the pathogenesis of multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). T-cell activation is controlled by a range of intracellular signaling pathways regulating cellular responses such as proliferation, cytokin...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Manresa-Arraut, Alba, Johansen, Flemming Fryd, Brakebusch, Cord, Issazadeh-Navikas, Shohreh, Hasseldam, Henrik
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990621/
https://ncbi.nlm.nih.gov/pubmed/29904389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01235
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