Neuroprotective Effects of Proanthocyanidins, Natural Flavonoids Derived From Plants, on Rotenone-Induced Oxidative Stress and Apoptotic Cell Death in Human Neuroblastoma SH-SY5Y Cells

Proanthocyanidins (PA) are natural flavonoids widely present in many vegetables, fruits, nuts and seeds, and especially in grape seed. In the present study, we examined the neuroprotective effects of PA and the underlying molecular mechanism in rotenone model of Parkinson's disease (PD). We fou...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Ma, Jian, Gao, Shan-Shan, Yang, Hai-Jie, Wang, Mian, Cheng, Bin-Feng, Feng, Zhi-Wei, Wang, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990600/
https://ncbi.nlm.nih.gov/pubmed/29904339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00369
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