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Neuroprotective effect of Demethoxycurcumin, a natural derivative of Curcumin on rotenone induced neurotoxicity in SH-SY 5Y Neuroblastoma cells

BACKGROUND: Mitochondrial dysfunction and oxidative stress are the main toxic events leading to dopaminergic neuronal death in Parkinson’s disease (PD) and identified as vital objective for therapeutic intercession. This study investigated the neuro-protective effects of the demethoxycurcumin (DMC),...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Ramkumar, Muthu, Rajasankar, Srinivasagam, Gobi, Veerappan Venkatesh, Dhanalakshmi, Chinnasamy, Manivasagam, Thamilarasan, Justin Thenmozhi, Arokiasamy, Essa, Musthafa Mohamed, Kalandar, Ameer, Chidambaram, Ranganathan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395846/
https://ncbi.nlm.nih.gov/pubmed/28420370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-017-1720-5
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