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Isobaric tag-based protein profiling of a nicotine-treated alpha7 nicotinic receptor-null human haploid cell line

Nicotinic acetylcholine receptors (nAChR), the primary cell surface targets of nicotine, have implications in various neurological disorders. Here we investigate the proteome-wide effects of nicotine on human haploid cell lines (wildtype HAP1 and α7KO-HAP1) to address differences in nicotine-induced...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Paulo, Joao A., Gygi, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990481/
https://ncbi.nlm.nih.gov/pubmed/29663646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201700475
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