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Evaluating the contribution of genetic and familial shared environment to common disease using the UK Biobank

Genome-wide association studies have detected many loci underlying susceptibility to disease, but most of the genetic factors that contribute to disease susceptibility remain unknown. Here we provide evidence that part of the missing heritability can be explained by an overestimation of heritability...

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Podrobná bibliografie
Vydáno v:Nat Genet
Hlavní autoři: Muñoz, María, Pong-Wong, Ricardo, Canela-Xandri, Oriol, Rawlik, Konrad, Haley, Chris S., Tenesa, Albert
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989924/
https://ncbi.nlm.nih.gov/pubmed/27428752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3618
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