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Evaluating the contribution of genetic and familial shared environment to common disease using the UK Biobank

Genome-wide association studies have detected many loci underlying susceptibility to disease, but most of the genetic factors that contribute to disease susceptibility remain unknown. Here we provide evidence that part of the missing heritability can be explained by an overestimation of heritability...

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Pubblicato in:Nat Genet
Autori principali: Muñoz, María, Pong-Wong, Ricardo, Canela-Xandri, Oriol, Rawlik, Konrad, Haley, Chris S., Tenesa, Albert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989924/
https://ncbi.nlm.nih.gov/pubmed/27428752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3618
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