Poorly neutralizing polyclonal antibody in vitro against coxsackievirus A16 circulating strains can prevent a lethal challenge in vivo

Neutralizing antibodies (NTAbs) is a major criterion for evaluation the immunogenicity of many vaccines, for example, poliovirus and EV71 vaccine. Here, we firstly discovered that polyclonal antibodies induced by inactivated CVA16 vaccine and lived CVA16 virus have poor ability to neutralize circula...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Hum Vaccin Immunother
Κύριοι συγγραφείς: Yao, Xin, Mao, QunYing, Li, Yajing, Hao, Chunsheng, Bian, LianLian, Chen, Pan, Gao, Fan, Wu, Xing, Lu, WeiWei, Gao, Qiang, Li, XiuLing, Liang, Zhenglun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Taylor & Francis 2018
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989894/
https://ncbi.nlm.nih.gov/pubmed/29337652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2018.1426420
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