Poorly neutralizing polyclonal antibody in vitro against coxsackievirus A16 circulating strains can prevent a lethal challenge in vivo

Neutralizing antibodies (NTAbs) is a major criterion for evaluation the immunogenicity of many vaccines, for example, poliovirus and EV71 vaccine. Here, we firstly discovered that polyclonal antibodies induced by inactivated CVA16 vaccine and lived CVA16 virus have poor ability to neutralize circula...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Yao, Xin, Mao, QunYing, Li, Yajing, Hao, Chunsheng, Bian, LianLian, Chen, Pan, Gao, Fan, Wu, Xing, Lu, WeiWei, Gao, Qiang, Li, XiuLing, Liang, Zhenglun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989894/
https://ncbi.nlm.nih.gov/pubmed/29337652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2018.1426420
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