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Activation of an unconventional meroterpenoid gene cluster in Neosartorya glabra leads to the production of new berkeleyacetals

Fungal genomes carry many gene clusters seemingly capable of natural products biosynthesis, yet most clusters remain cryptic or down-regulated. Genome mining revealed an unconventional paraherquonin-like meroterpenoid biosynthetic gene cluster in the chromosome of Neosartorya glabra. The cryptic or...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Zhang, Tao, Wan, Jun, Zhan, Zhajun, Bai, Jian, Liu, Bingyu, Hu, Youcai
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989830/
https://ncbi.nlm.nih.gov/pubmed/29881687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2017.12.005
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