Characterization of the unconventional meroterpenoid gene cluster from Stachybotrys sp. CPCC 401591 for phenylspirodrimanes biosynthesis

Abstract Background Phenylspirodrimanes (PSDs) are a unique class of meroterpenoids that have been extensively studied due to their diverse biological activities. These metabolites are supposedly biosynthesized through the farnesylation of orsellinate. However, the molecular basis has not yet been e...

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Autores principales:	Hui Lv, Bailin Song, Lingjin Bu, Wenni He, Lu Wang, Liyan Yu, Tao Zhang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-10-01
Colección:	Microbial Cell Factories
Materias:	Phenylspirodrimanes Genome mining Gene deletion Transcriptome Biosynthesis Stachybotrys
Acceso en línea:	https://doi.org/10.1186/s12934-025-02853-3
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