Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types

BACKGROUND: Single-cell genomic methods now provide unprecedented resolution for characterizing the component cell types and states of tissues such as the epithelial subsets of the gastrointestinal tract. Nevertheless, functional studies of these subsets at scale require faithful in vitro models of...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Biol
Main Authors: Mead, Benjamin E., Ordovas-Montanes, Jose, Braun, Alexandra P., Levy, Lauren E., Bhargava, Prerna, Szucs, Matthew J., Ammendolia, Dustin A., MacMullan, Melanie A., Yin, Xiaolei, Hughes, Travis K., Wadsworth, Marc H., Ahmad, Rushdy, Rakoff-Nahoum, Seth, Carr, Steven A., Langer, Robert, Collins, James J., Shalek, Alex K., Karp, Jeffrey M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989470/
https://ncbi.nlm.nih.gov/pubmed/29871632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0527-2
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki