Small molecule mimetics of α-helical domain of IRAK2 attenuate the pro-inflammatory effects of IL-33 in asthma-like mouse models

Interleukin-33 (IL-33) and its receptor ST2 play important roles in airway inflammation and contribute to asthma onset and exacerbation. IL-33/ST2 signaling pathway recruits adapter protein myeloid differentiation primary response 88 (MyD88) to transduce intracellular signaling. MyD88 forms a comple...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Li, Jinghong, Saruta, Kunio, Dumouchel, Justin P., Magat, Jenna M., Thomas, Joanna L., Ajami, Dariush, Rebek, Mitra, Rebek, Julius, Bigby, Timothy D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988972/
https://ncbi.nlm.nih.gov/pubmed/29728508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700693
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